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Is Niacinamide Good For Psoriasis

Niacin Niacinamide And Nicotinic Acid: What Is The Difference


Despite sounding the same, niacin , niacinamide , and nicotinic acid are different forms of vitamin B3.

Niacin is available as an oral supplement. However, your body can make niacinamide from the niacin supplements you take. Nicotinic acid and niacinamide are available as topical solutions. The skin has nicotinic acid receptors, and as a result, nicotinic acid has a drug-mediated effect on the skin . It causes vasodilation , resulting in skin flushing. It may also affect blood pressure, body temperature, and pulse rate.

Niacinamide or nicotinic acid has no side effects and is widely used and studied for its multiple skin benefits compared to nicotinic acid. Lets take a look.

The Ordinary Niacinamide 10% + Zinc 1% Oil Control Serum $12 To $14

Known for its no-frills, ingredients-and-thats-it approach, The Ordinary has phenomenal budget serums that do the job of improving your skin in whatever benefit youre seeking.

The combination of zinc with niacinamide makes this a true skin-calming agent. Mariwalla chimes in. Its great for people with redness or skin sensitivity who are also looking to make their pores smaller, but cant tolerate a retinoid.

Plus, Mudgil recommends this product for helping to reduce the faces oiliness.

Are There Any Risks Of Using Niacinamide

No. Niacinamide is one of the safest ingredients in the skin care industry. However, if you are using it for the first time, you may experience mild redness, itching, and burning sensations. However, that goes away once your skin gets used to it. Most of the users have never experienced any side effects.

Niacinamide is a skin-friendly ingredient, and you can combine it with almost all other active ingredients. Using niacinamide for skin may help improve your skin barrier resilience, reduce the appearance of aging signs, maintain skin hydration, even out your skin tone, reduce excess sebum, and prevent acne. If you have dry and sensitive skin, combine it with moisturizers, serums, oils, and other products you use to reap its maximum benefits. However, if you are new to niacinamide, start using it at a lower concentration. When used correctly, niacinamide can be your one-stop solution for maintaining healthy and bright skin.

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Consider A Medication Change

If youre struggling with an overload of flakes, you may need to evaluate and possibly switch medication. That can be frustrating, but there are many choices of targeted treatments on the market. It can be trial and error, but everyone can be treated, says Dr. Wechsler.

Psoriasis can be mild, moderate, or very severe, and these symptoms can change over time, so treatment that worked for you in the past may not be right for you now. If youre currently being treated for mild psoriasis but are starting to have more severe disease, talk to your doctor about if its time to change your therapy. Heres a brief overview of different types of treatment for psoriasis.

Should You Introduce Niacinamide Into Your Skincare Routine

Psoriasis Treatment &  Relief

Curious to find out whether niacinamide is worth trying for your skin? Take the test!

  • Is your skin prone to hyperpigmentation ?
  • Are you struggling with pimple marks ?
  • Do you wish to reduce dark circles or shadows under the eyes?
  • Is your skin tone uneven ?

If you have answered one or more of these questions with Yes!, we suggest taking a closer look at the following products.

Also Check: Is Plaque Psoriasis An Autoimmune Disorder

What Can You Use Niacinamide For

The most common use for niacinamide is to treat skin issues, such as acne, wrinkles, and fine lines, sun damage, redness, and hyperpigmentation.

Niacinamide can also improve your skins moisture barrier, which in turn increases hydration. It does this by increasing the level of lipids produced in the inner layer of the skin.

Skin Irritation And Inflammation


A topical gel containing niacinamide reduced skin peeling, redness, lesions, and irritation while increasing hydration and the skin barrier health in clinical studies of over 75 people with rosacea .


Topical niacinamide together with a synthetic form of vitamin D improved psoriasis in 50% of the cases in a clinical study on 66 people, compared to a 19% response with placebo .

Seborrheic Dermatitis

In 48 patients with facial seborrheic dermatitis, niacinamide 4% cream reduced the symptoms such as redness and scaling by 75%, compared to a 35% reduction with a placebo cream .

Atopic Dermatitis

Niacinamide 2% cream reduced skin water loss and improved skin hydration in 28 patients with atopic dermatitis .


Based on cellular studies, it might soothe irritated and inflamed skin by lowering inflammatory compounds .

Additionally, niacinamide can block the growth of fungi causing skin yeast infections .

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Can Psoriasis Be Managed By Only Using Topical Treatments

You may find that what works for you today stops working for you a year from now. Topicals such as creams and ointments can be very effective for reducing or even eliminating symptoms. However, theyre not a cure.

Avoiding triggers can help make topical treatments more effective. In some instances, they may also be more beneficial when combined with prescribed medications and changes to your nutrition.

Is Niacinamide The Same Thing As Niacin

Fade Acne Marks: How To Treat Post-Inflammatory Hyperpigmentation | Dr Sam Bunting

Niacinamide and niacin might sound similar but they vary greatly in their structure and makeup. They both have the same benefits, but niacinamide is a more stable form of vitamin B3 that can be used in higher doses than its counterpart.

Niacinamide promotes healthy skin by reducing inflammation, preventing age spots, and evening skin tone. It also supports circulation in the skin, which helps with many skin conditions, like rosacea and dermatitis.

Niacin has similar effects on your skin when applied topically, but it can cause stomach upset if used in high doses. For these reasons, niacinamide is preferred for topical application, while niacin is better for oral use.

Read Also: Difference Between Dry Skin And Psoriasis

Stress Lack Of Sleep And Other Lifestyle Factors

Some patients will report that certain dietary habits or stress make skin flaking worse, while others say that those factors have no impact. For example, in one study published in 2018 in theInternational Journal of Dermatologyup to 88 percent of cases pointed to stress as a trigger for their psoriasis. There was also a higher incidence of psoriasis among patients who had experienced a traumatic event.

Some patients will report that certain dietary habits or stress make skin flaking worse, while others say that those factors have no impact. For example, in one study published in 2015 in the journal BMC Dermatology about half of patients surveyed said that stress caused psoriasis to get worse and could pinpoint a stressful period of their life that was linked to the onset of their disease.

The thing about psoriasis is that it has a mind of its own, says Dr. Wechsler. Psychological stress and lack of sleep certainly can make a flaking flare worse. Theres a vicious cycle where the symptoms of the disease make you stressed, anxious, and down, and you dont sleep as well. That, in turn, compromises skin healing, and the cycle repeats, she says.

What Does Niacinamide Do For Your Skin

If niacinamide is involved in most important cell functions, then theres nothing it cant cure, right? Well, noif every cellular process in our bodies could be perfected with vitamin supplements, we wouldnt need antibiotics or radiation therapy. That said, oral and topical niacinamide may have some actual benefits for skin health:

Ask a dermatologist what niacinamide does best, and the very first niacinamide benefit theyll list is probably skin cancer prevention. In a 2015 study in the New England Journal of Medicine, researchers gave 386 patients 500 mg of oral niacinamide or a placebo twice daily for a whole year. All of the participants had at least two non-melanoma skin cancers within the previous five years and, therefore, were at a high risk for developing another skin cancer. Results showed that during the study, there were 23% fewer new cases of skin cancer in the group that received niacinamide compared to those who got the placebo .3

Both Dr. Zampella and Laura Ferris, MD, PhD, associate professor in the department of dermatology at the University of Pittsburgh, told SELF they frequently suggest oral niacinamide to their patients with a high risk for non-melanoma skin cancers, and cited this study as the reason why.

So, there is some evidence that oral niacinamide can be helpful for skin health in this specific situation. But is topical niacinamide helpful too?

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How To Use Niacinamide On Skin

  • Cleanse your face with a gentle cleanser and water
  • Apply toner to close off pores and remove any cleanser residue.
  • Pat your face dry with a clean towel, then apply your product.
  • Using small circular motions, massage it into your skin for about 1 minute.
  • Wait for 10 minutes, then apply a moisturizer to act as an effective barrier between your skin and the atmosphere.
  • Apply sunscreen if desired.

Apply niacinamide to your skin after cleansing and toning but before moisturizing and applying sunscreen on your face.

Bha And Niacinamide Serums

CeraVe Psoriasis Skin Therapy Moisturizer Cream

Minimizing my skincare routine has been a game-changer. Applying too many actives, especially those at higher concentrations, can cause havoc on the barrier . I took inventory of the products I was using and only kept a few serums that tackled multiple skin concerns at once, like Just Breathe does. This balancing serum contains willow bark extract and niacinamide. As a precursor to salicylic acid, willow bark extract is a natural beta-hydroxy acid , which gently exfoliates the skin. Meanwhile, niacinamide’s anti-inflammatory properties can soothe the irritation that goes hand-in-hand with plaque.

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Acure Radically Rejuvenating Niacinamide Serum $18 To $20

As a great product at a great price point, Mudgil approves of this product as your countertop niacinamide serum. Plus, the addition of hemp seed oil offers light hydration, too.

After trying some of Acures products, we recommend using this after the brands Brightening Cleansing Gel and before the Day & Night Creams .

Using Niacinamide With Hyaluronic Acid

First of all, lets talk about hyaluronic acid. Hyaluronic acid is a natural part of your skin and helps to keep it hydrated and youthful. As you age, your hyaluronic acid diminishes. And so, your skin gets dry, loses its elasticity, and wrinkles start to appear.

Hyaluronic acid works by binding water and retaining it in the skin cells. In other words, it helps to keep your skin hydrated. Using it alongside niacinamide can help even more.

How to use niacinamide with HA for maximal results:

  • Wash face with a mild cleanser and water, then pat dry with a towel.
  • Apply niacinamide serum to your face, avoiding eye area, lips, mouth, and other sensitive areas.
  • After about 10 minutes, apply a thin layer of hyaluronic acid serum over the niacinamide serum for an added boost.
  • After another 10 minutes, apply a moisturizer and sunscreen of your choice.

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What You Need To Know About Psoriasis Niacinamide Psoriasis

Is Your Stomach to Blame?

Who would have thought that a severe psoriasis outbreak could start because of something going wrong inside of your stomach and intestines? Yet, new research developed by psoriasis expert Edgard Cayce shows a distinct link between a leaky gut and a scaly psoriatic episode. According to Cayce, the primary source of psoriasis can be found in the intestinal tract, where toxins are leached into the body. This causes the immune system to react by thickening the skin. At the same time, the skin tries to purge the toxins through its layers, which can cause scabs and sores to form.

Could Arthritis Be the Cuplrit?

The intestines arent the only link to psoriasis found by researchers arthritis seems to also contribute to it. As many as one-third of all psoriasis patients eventually develop some form of psoriatic arthritis. Unlike normal forms of arthritis, those with psoriatic arthritis do not exhibit a rheumatoid factor when their blood is tested. This indicates that the arthritic condition comes solely from either the psoriasis itself or the underlying cause of the skin affliction.

Could a Virus Be the Cause?

Arthritis has been linked to certain virus and so have other auto-immune disorders. This leads some researchers to think that psoriasis too may start with a virus, which is what kicks the immune system into overdrive.

Moisturizers For Psoriasis: How To Choose

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Over-the-counter moisturizers can be highly beneficial for treating and preventing the symptoms of psoriasis, such as flaking, itching, and redness. Moisturizers, also called emollients, help keep the skin hydrated and allow it to heal. They also cover, soothe, and protect small skin cracks and fissures. While an OTC moisturizer may not be a substitute for a prescription medication, it can be an additional tool in your toolbox of psoriasis treatment options. Your dermatologist can help you understand how OTC products fit into your psoriasis treatment plan.

When choosing an OTC moisturizer, keep in mind the two most effective ingredients in managing psoriasis symptoms: salicylic acid and coal tar. The U.S. Food and Drug Administration has approved both ingredients to treat psoriasis.

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Nicotinamide In The Treatment Of Psoriasis

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
First Posted : January 8, 2013Last Update Posted : January 8, 2013
  • Study Details
Condition or disease
Drug: Calcipotriol plus NicotinamideDrug: Calcipotriol Phase 2Phase 3
Layout table for study information

Study Type :
Primary Purpose: Treatment
Official Title: Evaluation of Topical Nicotinamide in Combination With Calcipotriol Compared With Calcipotriol Alone for the Treatment of Mild to Moderate Psoriasis.
Study Start Date :
  • Psoriasis severity Patients are visited by a dermatologist at baseline and then after the first and third month of therapy, and psoriasis severity is evaluated using the modified psoriasis area and severity index.
  • Patient’s satisfaction Patient’s satisfaction is evaluated at the end of the trial using a 10-point rating scale.
  • What Results Can You Expect

    As with any new skin care product, you probably wont see any significant results for several weeks.

    Although most of the available research describes noticeable improvements after four weeks of use, theres no exact timeline.

    You may see even more changes to your skin after eight weeks. This includes smoother, toned, and hydrated skin.

    If you dont see any changes within a couple of months, it may be time to consult with a dermatologist. They can assess your skin care routine and advise you on which products to use, dietary changes that may improve your skin health, and more.

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    Reduces Fine Lines And Wrinkles

    As we age, our collagen breaks down, causing wrinkles and fine lines. Niacinamide works against these signs of aging by promoting collagen production in the skin.

    Niacinamide also stimulates the production of new cells in your body, thus helping you to replace older, damaged cells. As these new cells replace old ones, youll notice fewer wrinkles and fine lines on your skin.

    What Are The Supplements That May Not Be Good For Psoriasis

    Niacinamide, Vitamin B

    Most of the supplements have a good impact on the skin, but if you do not take supplements properly or take more supplements, it can have many side effects. You should always discuss which supplement is good for your skin and bring it under a doctors supervision as some accessories may suit you but not suit another person because of different skin types.

    What to keep in mind before using supplements?

  • Some supplements may cause an allergic reaction. So, the person using this supplement must always discuss with their dermatologist if they have any allergies.
  • It can also lead to severe hypersensitivity reactions, drug interactions, adverse effects on the liver, high blood pressure, etc. Hence, it is necessary to keep in mind these things before starting a new supplement.
  • If you are experiencing any other condition, you must first talk to your dermatologist before taking any supplemental medicine because all products are different and work differently on different peoples skin types hence before using any product, please consult with the doctor.
  • Always go for natural products as far as possible instead of artificial chemicals because too many chemicals are also not good for the skin.
  • It is always better to avoid chemical treatments and supplements unless a dermatologist orders them. Some people may have severe allergic reactions that you will never know until you use it on your skin or after its use.
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    Niacinamide Eases Rosacea Inflammation

    Niacinamide can be an effective treatment for the inflammation related to rosacea, according to Helen M. Torok, M.D. The etiology of rosacea is unknown, although research has shown that symptoms are exacerbated by factors that trigger innate responses, such as the release of cathelicidin antimicrobial peptides.

    Can Niacinamide Stop Oily Skin

    Niacinamide is one of the most effective ingredients for oily skin because it reduces the rate of sebum production. Thats why its become a favorite ingredient in oily skin products, including serums, moisturizers, and masks.

    While its no magic treatment for getting rid of oily skin, niacinamide has great benefits for oily skin types. This includes reducing the appearance of both acne and pore size, and regulating the production of sebum, Dr. Judith Hellman explains.

    So, how does it work? Niacinamide increases the rate of cell turnover while also increasing collagen production. Both factors combine to reduce oil production and breakouts while also improving the overall quality and texture of your skin.

    However, for niacinamide to be effective in getting rid of oily skin, it needs a complementary ingredient like salicylic acid or benzoyl peroxide that can draw out excess oil and impurities from pores, Hellman explains further.

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