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What Causes Severe Plaque Psoriasis

What Type Of Psoriasis Treatment Will I Need

A Solution for Your Plaque Psoriasis

Several treatment options can relieve psoriasis. Creams or ointments may be enough to improve the rash in small areas of skin. If the rash affects larger areas, or you also have joint pain, you may need other treatments. Joint pain may be a sign that you have arthritis.

Your provider will decide on a treatment plan based on:

  • Severity of the rash.
  • Vitamin A or retinoid creams.

Plaque Psoriasis Causes A Variety Of Symptoms

  • Plaque psoriasis appears on the skin as raised, red patches covered with a silvery buildup of dead skin cells
  • Patches are often silvery white, flaky, and scalyand can be itchy and painful
  • It most commonly appears on the knees, elbows, lower back, and scalp
  • It can also appear on the hands, feet, eyelids, ears, mouth, and lips

Can A Diet Cure Psoriasis Naturally

  • Avoiding environmental factors that trigger psoriasis, such as smoking, and stress, may help prevent or minimize flare-ups of psoriasis. Sun exposure may help in many cases of psoriasis and aggravate it in others.
  • Alcohol is considered a risk factor for psoriasis, even moderate amounts of beer. People should minimize alcohol use if they have psoriasis. This is especially important if they are taking medications such as methotrexate or acitretin.
  • Specific dietary restrictions or supplements other than a well-balanced and adequate diet are not important in the management of plaque psoriasis.
  • Recently, some data has supported that an “anti-inflammatory” diet that is high in fruits and vegetables and low in saturated and trans fats may help manage psoriasis, although the value in preventing its onset is less certain.

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Causes And Risk Factors Of Psoriasis

Psoriasis, in general, is a genetic condition passed down through families. “It’s likely that multiple genes need to be affected to allow psoriasis to occur and that it’s frequently triggered by an external event, such as an infection,” says James W. Swan, MD, professor of dermatology at the Loyola University Stritch School of Medicine in Maywood, Illinois.

Certain risk factors, such as a family history or being obese, may increase your odds of developing psoriasis.

According to the National Psoriasis Foundation , at least 10 percent of people inherit genes that could lead to psoriasis, but only 3 percent or less actually develop the disease. For this reason, it is believed that the disease is caused by a combination of genetics and external factors or triggers.

A psoriasis outbreak may be provoked by:

Medical Treatment Topical Agents

Plaque Psoriasis What Causes It

The first line of treatment for psoriasis includes topical medications applied to your skin. The main topical treatments are corticosteroids , vitamin D-3 derivatives, coal tar, anthralin, and retinoids. These drugs may lose potency over time, so often they are rotated or combined. Ask your doctor before combining medications, as some drugs should not be combined.

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What Psoriasis Creams And Topical Agents Can I Use

Medications applied directly to the skin are the first line of treatment options for psoriasis.

The main topical treatments are:

  • corticosteroids,
  • anthralin, or
  • retinoids.

For more detailed information on each medication, see Understanding Psoriasis Medications. Generic drug names are listed below with examples of brands in parentheses.

Topical Medications

  • Corticosteroids: Topical corticosteroids are the mainstay of treatment in mild or limited psoriasis and come in a variety of forms. Foams and solutions are best for scalp psoriasis and other thickly hair-bearing areas, such as a hairy chest or hairy back. Creams are usually preferred by patients, but ointments are more potent than any other vehicles, even at the same percentage concentration.
  • Super potent topical corticosteroids such as clobetasol propionate and betamethasone dipropionate augmented are commonly prescribed corticosteroids for use on non-facial, non-intertriginous areas .
  • As the condition improves, one may be able to use potent steroids such as:
  • mometasone furoate or
  • halcinonide or
  • mid-potency steroids such as triamcinolone acetonide or betamethasone valerate . These creams or ointments are usually applied once or twice a day, but the dose depends on the severity of the psoriasis as well as the location and thickness of the plaque.

Scalp Psoriasis Vs Dermatitis

Dermatitis is a term used to describe various types of skin inflammation. This includes contact dermatitis as well as seborrheic dermatitis .

Like psoriasis, dermatitis can also affect the scalp. While some of the treatments for these conditions may overlap, the conditions themselves have different causes.

Scalp psoriasis is likely caused by immune dysfunction. Dermatitis is caused by various skin irritants, such as allergens.

With scalp psoriasis, youll notice silvery-red scales that may extend beyond the hairline. Theyll cause itching, flaking, and redness. In dermatitis, scales are white or yellowish and accompanied by dandruff.

A doctor can usually tell the difference between scalp psoriasis and dermatitis by taking a look at the affected area. In other cases, it might be trickier to tell the difference.

They might perform a skin scrape or take a biopsy. An overgrowth of skin cells will be present in cases of scalp psoriasis. In dermatitis cases, there will be irritated skin and sometimes bacteria or fungi.

Dermatitis can cause dandruff. Scalp psoriasis and dandruff share many of the same symptoms, such as:

  • white or yellow skin flakes on the scalp
  • mild redness

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When To See A Doctor

Anyone who notices unusual changes in their skin should see a doctor.

Individuals with a diagnosis of psoriasis should follow their treatment plan and see their doctor if symptoms persist or worsen, or if treatment results in adverse effects.

There is currently no cure for plaque psoriasis, but many treatment options are available, depending on the individual and the severity of symptoms.

Options include:

  • reduce dryness and cracking
  • improve itching

Various topical treatments are available from a pharmacist or for purchase online, with or without a prescription.

It is best to check first with a doctor or pharmacist before choosing a topical treatment, as some may suit an individual better than others. In certain cases, there may not be enough scientific evidence to confirm that they are safe to use or work.

Talk With Others Who Understand

The invisible impact of moderate-to-severe plaque psoriasis

MyPsoriasisTeam is the social network for people with psoriasis and their loved ones. On MyPsoriasisTeam, more than 88,000 members come together to ask questions, give advice, and share their stories with others who understand life with psoriasis.

Are you living with plaque psoriasis? How do you manage your symptoms? Share your experience in the comments below, or start a conversation by posting on your Activities page.

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Research And Statistics: Who Has Psoriasis

According to the National Psoriasis Foundation, about 7.5 million people in the United States have psoriasis. Most are white, but the skin disease also affects Black, Latino, and Asian Americans as well as Native Americans and Pacific Islanders.

The disease occurs about equally among men and women. According to the National Institutes of Health , it is more common in adults, and you are at a greater risk if someone in your family has it. A study published in September 2016 in the journal PLoS One concluded that interactions between particular genes as well as genetic and environmental factors play an important role in the diseases development.

People with psoriasis generally see their first symptoms between ages 15 and 30, although developing the disease between 50 and 60 years of age is also common.

The biggest factor for determining prognosis is the amount of disease someone has, says Michael P. Heffernan, MD, a dermatologist at the San Luis Dermatology and Laser Clinic in San Luis Obispo, California.

What Are The Types Of Psoriasis

In children, common types of psoriasis include:

Plaque psoriasis. This is the most common type of psoriasis. It causes plaques and silvery scales, usually on the knees, elbows, lower back, and scalp. They can be itchy and painful and may crack and bleed.

Guttate psoriasis. This type often shows up after an illness, especially strep throat. It causes small red spots, usually on the trunk, arms, and legs. Spots also can appear on the face, scalp, and ears.

Inverse psoriasis. This causes smooth, raw-looking patches of red skin that feel sore. The patches develop in places where skin touches skin, such as the armpits, buttocks, upper eyelids, groin and genitals, or under a woman’s breasts.

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Plaque Psoriasis And Its Reach: The Scalp And Beyond

According to the American Academy of Dermatology, at least 50 percent of people with plaque psoriasis will experience a bout of scalp psoriasis. Plaque psoriasis on the scalp may require different treatment than plaque psoriasis on other parts of the body.

Medicated ointments, shampoos, and careful removal of scales can help treat scalp psoriasis. Sometimes, systemic medications must be used to clear plaque psoriasis on the scalp.

What You Can Do

Chronic

Most people who get plaque psoriasis have it for the rest of their lives. You can do a few things to deal with it better:

Avoid triggers. Things like stress and smoking don’t cause psoriasis. But they can make it worse. Try to figure out what triggers your flare-ups. You may be affected by:

  • Alcohol

American Academy of Dermatology: “Psoriasis.”

Medscape: “FDA OKs Biologic Guselkumab for Plaque Psoriasis.” “Plaque Psoriasis.”

National Institute of Arthritis and Musculoskeletal and Skin Diseases: “Psoriasis.”

National Psoriasis Foundation.

UpToDate: “Treatment of psoriasis.”

Weigle, N., American Family Physician, May 2013.

Bruce E. Strober, MD, PhD. associate director of Dermatopharmacology, Department of Dermatology, New York University School of Medicine co-director of the Psoriasis and Psoriatic Arthritis Center consultant for Amgen, Biogen, Genentech, Fujisawa, and 3-M.

Jeffrey M. Weinberg, MD, director of the Clinical Research Center, St. Luke’s-Roosevelt Hospital Center, New York City assistant clinical professor of dermatology, Columbia University College of Physicians and Surgeons consultant for Amgen and Genentech.

Abel, E. “Dermatology III: Psoriasis,” ACP Medicine, April, 2005.

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Generalised Pustular Psoriasis Or Von Zumbusch Psoriasis

This causes pustules that develop very quickly on a wide area of skin. The pus consists of white blood cells and is not a sign of infection.

The pustules may reappear every few days or weeks in cycles. During the start of these cycles, von Zumbusch psoriasis can cause fever, chills, weight loss and fatigue.

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Light Treatment For Plaque Psoriasis

Light therapy is a common treatment for plaque psoriasis. Because light therapy is nonpharmaceutical, its a popular choice prior to systemic medications.

Some people are able to achieve healing through regular limited sessions of sun exposure, while others fare better using a special light machine.

Check with your dermatologist before treating your psoriasis through exposure to sunlight. Too much sun exposure can burn your skin and make plaque psoriasis worse.

What Kind Of Doctor Treats Psoriasis

Improving Outcomes for Patients With Moderate to Severe Plaque Psoriasis

There are several types of doctors who may treat psoriasis. Dermatologists specialize in the diagnosis and treatment of skin disorders, including psoriasis. Rheumatologists specialize in the treatment of joint disorders, including psoriatic arthritis. Family physicians, internal medicine physicians, rheumatologists, dermatologists, and other medical doctors may all be involved in the care and treatment of patients with psoriasis.

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What Causes Severe Plaque Psoriasis

plaque psoriasiscauses

. Then, what is severe plaque psoriasis?

Plaque psoriasis. Plaque psoriasis is a chronic autoimmune condition. It appears on the skin in patches of thick, red, scaly skin. Plaque psoriasis can be a very itchy and sometimes painful condition. It also can be embarrassing and doesn’t always respond to treatment.

Beside above, how do you get rid of plaque psoriasis? Avoid harsh or scented soaps, which can strip the skin’s natural oils. After bathing, gently remove the skin with your fingers, tweezers, or wet washcloth. You can also use a pumice stone or nail file on very thick scales. But take extra care not to tear or damage the skin beneath.

In this manner, what is the main cause of plaque psoriasis?

The sped-up skin cell production causes new skin cells to develop too quickly. They are pushed to the skin’s surface, where they pile up. This results in the plaques that are most commonly associated with psoriasis. The attacks on the skin cells also cause red, inflamed areas of skin to develop.

How long do psoriasis plaques last?

Once a person has had a psoriasis flare, they are likely to have another one. Patches of psoriasis may clear up after a few months, or they may stay the same, get bigger, or spread across the body. In some people, psoriasis will disappear and not return for years.

Are There Complications Of Psoriasis

In some people, psoriasis causes more than itchiness and red skin. It can lead to swollen joints and arthritis. If you have psoriasis, you may be at higher risk of:

  • Use medicated shampoo for scales on your scalp.

Other steps you should take to stay as healthy as possible:

  • Talk to your healthcare provider about lowering your risk for related conditions, such as heart disease, depression and diabetes.
  • Lower your stress with meditation, exercise or seeing a mental health professional.

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Natural Skin Treatments For Plaque Psoriasis

Because its a chronic condition, many people with plaque psoriasis will try alternative and natural treatment methods. One method that has gained significant attention in the psoriasis community is the mud and salt of the Dead Sea.

Thousands of people a year invest in expensive Dead Sea skin treatments or vacations to attempt to heal their psoriasis. Although the scientific evidence is limited regarding the effectiveness of these treatments, many believe it can help treat plaque psoriasis.

What Injections Or Infusions Are Available For Psoriasis

What Causes Chronic Plaque Psoriasis

Recently, a new group of drugs called biologics have become available to treat psoriasis and psoriatic arthritis. They are produced by living cells cultures in an industrial setting. They are all proteins and therefore must be administered through the skin because they would otherwise be degraded during digestion. All biologics work by suppressing certain specific portions of the immune inflammatory response that are overactive in psoriasis. A convenient method of categorizing these drugs is on the basis of their site of action:

  • T cell inhibitor abatacept
  • Drug choice can be complicated, and your physician will help in selecting the best option. In some patients, it may be possible to predict drug efficacy on the basis of a prospective patient’s genetics. It appears that the presence of the HLA-Cw6 gene is correlated with a beneficial response to ustekinumab.

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    Enhancing Healthcare Team Outcomes

    Plaque psoriasis is a complex life long disorder with enormous morbidity. Thus, it is best managed by an interprofessional team.

    Insulin resistance and cardiovascular diseases are more common in psoriatic patients as are metabolic comorbidities. Obesity is the most common comorbidity observed in children with psoriasis. Many patients present with reduced quality of life and psychological manifestations and need special attention and counseling. Thus, primary care clinicians should advocate lifestyle modification such as reducing weight, reducing alcohol intake and smoking cessation may help control psoriasis, improve the results of treatment and prevent future complications.

    Sudden onset, palmoplantar keratoderma, severe nail dystrophy, the involvement of skin folds should arouse suspicion of associated HIV infection in whom pustular forms are also more common with a higher frequency of arthritis.

    Teaching Points

    Outcomes

    Can Psoriasis Affect Only My Nails

    In some cases, psoriasis may involve only the fingernails and toenails, although more commonly, nail symptoms will accompany psoriasis and arthritis symptoms. The appearance of the nails may be altered, and affected nails may have small pinpoint pits or large yellow-colored separations on the nail plate called oil spots. Nail psoriasis can be hard to treat but may respond to medications taken for psoriasis or psoriatic arthritis. Treatments include topical steroids applied to the cuticle, steroid injections at the cuticle, or oral medications.

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    Plaque Psoriasis: Diagnosis Symptoms And Treatment

    • Plaque psoriasis affects around 90 percent of people with psoriasis.
    • Most people are diagnosed between the ages of 20 and 30 or between 50 and 60.
    • The thick, scaly lesions of plaque psoriasis are caused by the overproduction of skin cells.
    • Treatment includes phototherapy and topical, oral, and injected medications.

    Plaque psoriasis is the most common type of psoriasis and affects between 80 percent and 90 percent of people with psoriasis. People with plaque psoriasis may also have another form of psoriasis, such as guttate psoriasis, inverse psoriasis, pustular psoriasis, or erythrodermic psoriasis. Plaque psoriasis may also be associated with psoriatic arthritis.

    Plaque psoriasis is a skin condition characterized by thick, red or purple lesions with silvery scales on the skin and scalp. Lesions are formed from an abnormal buildup of skin cells.

    Plaque psoriasis is the skin manifestation of a chronic autoimmune condition caused by a dysfunction in the immune system. People with plaque psoriasis have an overactive immune system that causes an inflammatory reaction with T cells, causing skin cells to proliferate at an abnormally high rate.

    Plaque psoriasis can have a severe impact on quality of life, but it is not life-threatening. People with plaque psoriasis tend to have higher rates of cardiovascular disease, diabetes, and inflammatory bowel disease, among other comorbidities, which can cause complications that may decrease longevity.

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