Tuesday, July 9, 2024

What Is The Main Cause Of Plaque Psoriasis

What Causes Nail Psoriasis

Causes And Symptoms Of Psoriasis

Of all the people who have some type of psoriasis, up to 50% will also have nail psoriasis. Like scalp psoriasis, it often comes along with plaque psoriasis, but it can also accompany other types or appear all on its own, too. Those with psoriatic arthritis will have an 80% chance of having nail psoriasis, too.

The same underlying causes as plaque psoriasis are at play here, too, revving up your skin cell production. Nails are considered part of the skin , which is why they are also affected by the disease.

Racial Disparity In Psoriasis

Psoriasis can affect persons of any race however, epidemiologic studies have shown a higher prevalence in western European and Scandinavian populations. In these groups, 1.5-3% of the population is affected by the disease.

The highest documented disease prevalence is in Arctic Kasach’ye, with 12% of the population affected, followed by Norway, where 4.8% of the population has psoriasis. Lower prevalence rates for psoriasis have been reported among Japanese and Inuit populations.

Psoriasis is thought to be rare in West Africans and African Americans and is nearly absent in North American Indians. Psoriasis was undetected in the Samoan population and in a study that examined 26,000 South American Indians.

How Do You Treat Psa

If you have this condition, youll want to see a rheumatologist, a doctor who specializes in arthritis. Treatments can range OTC non-steroidal anti-inflammatory drugs such as Advil to disease-modifying antirheumatic drugs , including methotrexate, that work by slowing your immune system and your bodys inflammatory response. If those dont work, biologics may be considered.

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What Causes Severe Plaque Psoriasis

plaque psoriasiscauses

. Then, what is severe plaque psoriasis?

Plaque psoriasis. Plaque psoriasis is a chronic autoimmune condition. It appears on the skin in patches of thick, red, scaly skin. Plaque psoriasis can be a very itchy and sometimes painful condition. It also can be embarrassing and doesn’t always respond to treatment.

Beside above, how do you get rid of plaque psoriasis? Avoid harsh or scented soaps, which can strip the skin’s natural oils. After bathing, gently remove the skin with your fingers, tweezers, or wet washcloth. You can also use a pumice stone or nail file on very thick scales. But take extra care not to tear or damage the skin beneath.

In this manner, what is the main cause of plaque psoriasis?

The sped-up skin cell production causes new skin cells to develop too quickly. They are pushed to the skin’s surface, where they pile up. This results in the plaques that are most commonly associated with psoriasis. The attacks on the skin cells also cause red, inflamed areas of skin to develop.

How long do psoriasis plaques last?

Once a person has had a psoriasis flare, they are likely to have another one. Patches of psoriasis may clear up after a few months, or they may stay the same, get bigger, or spread across the body. In some people, psoriasis will disappear and not return for years.

What Are The Symptoms Of Psoriasis

Psoriasis

The following are the most common symptoms of psoriasis. Psoriasis comes in several forms and severities. Symptoms may include:

  • Plaque psoriasis. This type of psoriasis is the most common. Symptoms may include patches of red, raised skin on the trunk, arms, legs, knees, elbows, genitals, and scalp. Nails may also thicken, become pitted, and separate from the nail beds.

  • Guttate psoriasis. This type of psoriasis affects mostly children. Symptoms may include many small spots of red, raised skin. A sore throat usually proceeds the onset of this type of psoriasis.

  • Pustular psoriasis. Symptoms may include small pustules all over the body or just on the palms, soles, and other small areas.

The symptoms of psoriasis may look like other skin conditions. Always talk with your healthcare provider for a diagnosis.

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Inflammation And Psoriasis: Making The Connection

The immune system and inflammation play a role in psoriasis. Heres how theyre believed to be connected.

Think of the immune system as your bodys alarm system. When you get a cold, infection, or scrape on your knee, your immune system sends out signals that trigger inflammation in an effort to defend itself.

When you have psoriasis, your immune system is out of balance. In fact, its in overdrive. An overactive immune system can send faulty signals and mistake healthy cells for harmful ones. This results in too much inflammation. For psoriasis patients, this means the body rapidly produces more skin cells than necessary.

Luckily, some treatment options can reduce inflammation, which may help the immune system and help to slow the rapid production of skin cells.

Talk to a dermatologist to learn more about treatment options that may work for you.

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Its important to work with a dermatologist when choosing a psoriasis treatment. Learn how to start that conversation.

Ready To See If Cosentyx Can Help You Feel Real Relief From Your Symptoms

Find a dermatologist in your area who has experience prescribing biologics as well as other treatments for moderate to severe plaque psoriasis.

COSENTYX® is a prescription medicine used to treat:

  • people 6 years of age and older with moderate to severe plaque psoriasis that involves large areas or many areas of the body, and who may benefit from taking injections or pills or phototherapy

  • adults with active psoriatic arthritis

  • adults with active ankylosing spondylitis

  • adults with active non-radiographic axial spondyloarthritis and objective signs of inflammation

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients.

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections, sometimes serious.

  • Your doctor should check you for tuberculosis before starting treatment with COSENTYX.
  • If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.
  • Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX. Do not take COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

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What Causes Plaque Psoriasis

The cause for all cases of psoriasis stems from a combo of genetics, immune dysfunction, and triggers. People who have psoriasis are also more likely to have other inflammatory diseases such as Crohns disease, heart disease, or diabetes, suggesting some link between the underlying inflammation.

A study in Archives of Dermatology that looked at over 100,000 patients with psoriasis found those with severe psoriasis had a 46% greater chance of having diabetes than those without the skin disease.

What Causes Psoriasis Outbreaks

How does psoriasis start? Main Causes & Symptoms – Dr. Chaithanya K S | Doctors’ Circle

Psoriasis outbreaks differ from person to person. No one knows exactly what causes flare-ups. Common psoriasis triggers may include:

  • Skin injury .
  • Streptococcal or other infection that affects the immune system.
  • Certain prescription medications .
  • Cold weather, when people have less exposure to sunlight and humidity and more to hot, dry indoor air.

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How Long Does It Take For Plaque Psoriasis To Heal

Although research is promising, doctors cannot yet cure psoriasis. Once a person has had a psoriasis flare, they are likely to have another one.

Patches of psoriasis may clear up after a few months, or they may stay the same, get bigger, or spread across the body. In some people, psoriasis will disappear and not return for years.

Treatment can help reduce the frequency of flares and the severity of symptoms.

People who find that environmental factors trigger their flares can often reduce flare frequency by controlling these triggers, which may include stress or allergies.

Psoriasis has a characteristic appearance that most doctors quickly recognize.

If a doctor suspects psoriasis but is unsure, they may perform a skin biopsy to rule out other causes. The biopsy will involve taking a sample of affected skin and examining it under a microscope.

Treatment depends on the severity of psoriasis. Some people can control their symptoms by avoiding triggers and using over-the-counter corticosteroid creams.

People with moderate or severe psoriasis may need medication to control their symptoms. A wide range of medications is available, including:

Other treatment strategies include:

other types of psoriasis include:

What Is The Best Psoriasis Treatment

Many prescription-strength psoriasis medications that are effective at managing psoriasis. For mild or controlled cases, medications applied directly to the skin may be appointed:

The backbone of therapy for psoriasis is limited steroids, both in creams or lotion form. Higher power scalp psoriasis treatment steroids are used for the body or scalp, and lower-potency topical steroids are most suitable for the face and skin fold regions. Steroid juices or liquids can be used on the scalp. Use should be checked to 1â4 weeks at a time because long-term use of steroids can drive to stretch marks and weaken the skin.

Calcipotriene is a vitamin D derivative lotion that acts as well as steroids, and it is even more useful when coupled with topical steroids.

Tazarotene is a vitamin A-based cream that may be appointed. Women who are pregnant should be advised to avoid pregnancy while using tazarotene because this therapy may cause birth deformities.

Topical immune suppressants such as tacrolimus and pimecrolimus may also be applied, but they can cause skin burning and itching and are costly. These treatments may raise your chance of skin cancer and lymphoma.

Coal tar-based treatments and anthralin psoriasis cream are sometimes used. However, they are used more frequently than other therapies because they have a smell, cause skin inflammation, and can stain clothing and because they arent any more powerful than calcipotriene.

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Doctor’s Notes On Psoriasis

Psoriasis is a chronic autoimmune skin disorder that causes patchy, red, scaly areas of skin. It typically affects the arms, legs, trunk, scalp, knees, elbows, and lower back but it may occur on any part of the skin. The most common form of psoriasis is called plaque psoriasis .

Symptoms of plaque psoriasis include

  • plaques that are red, raised,
  • scaly skin affecting the scalp, elbows, and knees.
  • The plaques may itch or burn.
  • Flares may last weeks to months.
  • Plaques may split and bleed, especially when they occur over joints or on the palms or feet.
  • Plaques may be surrounded by a halo or ring of blanched skin .
  • Skin scales are silvery white and thickness varies.

Other symptoms of psoriasis include

  • nail changes such as discoloration and separation from the nail bed at the fingertip.

In children, symptoms of plaque psoriasis may appear different. Plaques are not as thick and the affected skin is less scaly. Psoriasis often appears in the diaper region in infancy and in flexural areas and the face in children.

What Is the Treatment for Psoriasis?

There is no cure for psoriasis, but treatments can relieve symptoms and decrease flare-ups.

Medical treatments for psoriasis include:

  • Topical treatments
  • Over-the-counter topical treatments
  • Ultraviolet light B : broad band and narrow band
  • Systemic treatments
  • Biologics and biosimilars
  • Tumor necrosis factor-alpha inhibitors such as certolizumab pegol , etanercept , adalimumab , infliximab , golimumab
  • T-cell inhibitors such as Orencia
  • What Else Should I Ask My Healthcare Provider

    What Causes Psoriasis On Hairline Treatment Prognosis ...

    If you have psoriasis, ask your healthcare provider:

    • How can I prevent outbreaks and control symptoms?
    • What medication will work best for me?
    • What else should I do to improve symptoms?
    • What are my options if creams dont work?
    • Will psoriasis ever go away?

    A note from Cleveland Clinic

    Psoriasis, an itchy skin condition, can come and go throughout your life. Its related to an overactive immune response and is not contagious. If you have skin changes that arent going away, talk to your healthcare provider. There is no cure for psoriasis, but psoriasis treatments can improve symptoms. Your provider may prescribe a special cream or moisturizer or medications. Other therapies are available if creams or medicines dont work. Maintaining your overall health will also help improve symptoms.

    Last reviewed by a Cleveland Clinic medical professional on 10/17/2020.

    References

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    How Is Psoriasis Diagnosed And Treated

    Psoriasis often has a typical appearance that a primary care doctor can recognize, but it can be confused with other skin diseases , so a dermatologist is often the best doctor to diagnose it. The treatment of psoriasis usually depends on how much skin is affected, how bad the disease is , or the location . Treatments range from creams and ointments applied to the affected areas to ultraviolet light therapy to drugs . Many people who have psoriasis also have serious health conditions such as diabetes, heart disease, and depression. Some people with psoriasis also have an inflammatory condition which affects their joints, called psoriatic arthritis.

    Psoriatic arthritis has many of the same symptoms as other types of arthritis, so a rheumatologist is often the best doctor to diagnose it. The treatment of psoriatic arthritis usually involves the use of drugs .

    Psoriatic disease may be treated with drugs or a combination of drugs and creams or ointments.

    What Are The Symptoms Of Plaque Psoriasis

    Everybody experiences the symptoms of plaque psoriasis in different ways, which can vary based on the type of psoriasis, as well as the severity. However, common symptoms can include one or more of the following:

    • Reddish, raised areas of inflamed skin
    • Scaly, silver-colored patches in the inflamed areas
    • Cracked, dry skin that may bleed
    • Sore, itchy, or burning skin
    • Small, red spots

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    Is It Psoriasis Or Eczema

    Like psoriasis, eczema is a very itchy skin condition. In fact, eczema usually results in a more intense itch than psoriasis. Scratching causes inflammation of the skin, leading to a worsening of the eczema. Scratching can also cause a secondary bacterial infection.

    Eczema is not a specific disease, but rather a term referring to a group of rash-like conditions. The most common type of eczema is caused by a reaction to irritants, like detergents, soaps, or household cleansers.

    Eczema often shows up on the back of the knees or the inside of the elbows.

    Eczema can affect anyone and affects children more than psoriasis does.

    What Are Other Types Of Psoriasis

    Psoriasis Explained – What Causes Psoriasis and How To Treat Psoriasis !

    Plaque psoriasis is the most common type. About 80% to 90% of people with psoriasis have plaque psoriasis.

    Other, less common types of psoriasis include:

    • Inverse psoriasis appears in skin folds. It may look like thin pink plaques without scale.
    • Guttate psoriasis may appear after a sore throat caused by a streptococcal infection. It looks like small, red, drop-shaped scaly spots in children and young adults.
    • Pustular psoriasis has small, pus-filled bumps on top of the red patches or plaques.
    • Sebopsoriasis typically appears on the face and scalp as red bumps and plaques with greasy yellow scale. This type is a cross between psoriasis and seborrheic dermatitis.

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    Can Psoriasis Cause Dandruff

    People with scalp psoriasis may experience flaking from the scalp that can look very much like dandruff. Both can cause itching and flaking on the scalp however, dandruff is caused by a fungal infection and scalp psoriasis is an autoimmune condition9. Dandruff-like flaking happens when the layer of silvery scale covering the top of a plaque flakes off in small pieces. A range of medicated shampoos and topical treatments is available for softening and treating the scalp plaques to reduce the amount of flaking.

    For more information on the symptom of dandruff

    Knowing Your Risk For Psoriasis

    For those genetically predisposed to the disease, Dr. Cohen says that there are certain risk factors that can increase the odds of developing it.

    “Cigarette smoking, alcohol use, certain medications are environmental factors that might bring out psoriasis in someone who’s genetically susceptible,” says Dr. Cohen. And while genes or environmental factors can play a role in causing some people to develop the disease, the “exact mechanism” of why people get it remains a mystery, he adds.

    As sufferers know, flare-ups can come and go with little-to-no warning, but any number of possible triggers are thought to contribute to bouts with the disease. “When flares of psoriasis occur, the first thing that needs to be done is to identify the cause and rule out an infection as the triggering event,” says Dr. Gelfand.

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    What If Those Psoriasis Treatments Dont Work

    If psoriasis doesnt improve, your healthcare provider may recommend these treatments:

    • Light therapy: UV light at specific wavelengths can decrease skin inflammation and help slow skin cell production.
    • PUVA: This treatment combines a medication called psoralen with exposure to a special form of UV light.
    • Methotrexate: Providers sometimes recommend this medication for severe cases. It may cause liver disease. If you take it, your provider will monitor you with blood tests. You may need periodic liver biopsies to check your liver health.
    • Retinoids: These vitamin A-related drugs can cause side effects, including birth defects.
    • Cyclosporine: This medicine can help severe psoriasis. But it may cause high blood pressure and kidney damage.
    • Immune therapies: Newer immune therapy medications work by blocking the bodys immune system so it cant jumpstart an autoimmune disease such as psoriasis.

    What You Should Know About Plaque Psoriasis

    Symptoms of Psoriasis

    This is the type youre probably thinking of when someone mentions psoriasis. Its characterized by clearly demarcated, raised, red, scaly patches called plaques that appear most commonly on your elbows, knees, scalp, and back .

    Because it accounts for 80% of all cases, plaque psoriasis tends to get the most press. Its the type addressed in most psoriasis drug commercials, and celebs including reality star Kim Kardashian and singer Cyndi Lauper have both been vocal about being plagued with plaques.

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